The study reports on the results of an empirical investigation of the education and recruitment processes used in HIV vaccine trials conducted in South Africa. Interviews were conducted with 21 key informants involved in HIV vaccine research in South Africa and three focus groups of community advisory board members. Data analysis identified seven major themes on the relationship between education and recruitment: the process of recruitment, the combined dual role of educators and recruiters, conflicts perceived by field staff, pressure to (...) achieve recruitment targets, problems in achieving comprehension, accountability and education as capacity building. The results raise ethical concerns about the adequacy of current informed consent processes in these settings. The study findings bear directly on current debates about issues of exploitation and the scope of moral responsibilities of researchers and funding agencies to assure that HIV clinical prevention research is conducted ethically. (shrink)

This paper outlines the demographic characteristics of the Baiga tribe, one of the most primitive of the aboriginal tribal groups of Central India. The Baiga population has grown steadily since the first anthropological study of the tribe in the 1930s. Age at menarche, age at marriage, breast-feeding, and time interval between marriage and first conception are natural. There are more females than males. Sub-tribe endogamy is common; consanguineous marriage is favoured (34% of marriages are between first cousins) and marital distance (...) is low (mean 7·1 km). Though the mean menarcheal age is high (15·2 years), mean age at first marriage is low (16·6 years), giving a long reproductive period. (shrink)

According to prevailing theory, relativistic degenerate stars with masses beyond the Chandrasekhar and Oppenheimer–Volkoff (OV) limits cannot achieve hydrostatic equilibrium through either electron or neutron degeneracy pressure and must collapse to form stellar black holes. In such end states, all matter and energy within the Schwarzschild horizon descend into a central singularity. Avoidance of this fate is a hoped-for outcome of the quantization of gravity, an as-yet incomplete undertaking. Recent studies, however, suggest the possibility that known quantum processes may (...) intervene to arrest complete collapse, thereby leading to equilibrium states of macroscopic size and finite density. I describe here one such process which entails pairing (or other even-numbered association) of neutrons (or constituent quarks in the event of nucleon disruption) to form a condensate of composite bosons in equilibrium with a core of degenerate fermions. This process is analogous to, but not identical with, the formation of hadron Cooper pairs that give rise to neutron superfluidity and proton superconductivity in neutron stars. Fermion condensation to composite bosons in a star otherwise destined to collapse to a black hole facilitates hydrostatic equilibrium in at least two ways: (1) removal of fermions results in a decrease in the Fermi level which stiffens the dependence of degeneracy pressure on fermion density, and (2) phase separation into a fermionic core surrounded by a self-gravitating condensate diminishes the weight which must be balanced by fermion degeneracy pressure. The outcome is neither a black hole nor a neutron star, but a novel end state, a “fermicon star,” with unusual physical properties. (shrink)

"Sir Hermann Bondi, NatureThe late S. Chandrasekhar was best known for his discovery of the upper limit to the mass of a white dwarf star, for which he received ...

According to the Rayleigh criterion of classical optics, the finite resolving power of a microscope is due to the width of the central peak of the Fraunhofer diffraction pattern produced by the microscope's finite lens aperture. During the last few decades, theories and techniques for superresolution beyond the Rayleigh criterion have been developed in classical optics. Thus, Heisenberg's microscope could also in principle be made to give superresolution and thereby appear to violate the uncertainty relation. We believe that this paradox (...) is due to the inappropriate use of a definition, based purely on experimental convenience, to support a quantum mechanical theorem. (shrink)

Newton's Philosophiae Naturalis Principia Mathematica provides a coherent and deductive presentation of his discovery of the universal law of gravitation. It is very much more than a demonstration that 'to us it is enough that gravity really does exist and act according to the laws which we have explained and abundantly serves to account for all the motions of the celestial bodies and the sea'. It is important to us as a model of all mathematical physics.Representing a decade's work from (...) a distinguished physicist, this is the first comprehensive analysis of Newton's Principia without recourse to secondary sources. Professor Chandrasekhar analyses some 150 propositions which form a direct chain leading to Newton's formulation of his universal law of gravitation. In each case, Newton's proofs are arranged in a linear sequence of equations and arguments, avoiding the need to unravel the necessarily convoluted style of Newton's connected prose. In almost every case, a modern version of the proofs is given to bring into sharp focus the beauty, clarity, and breath-taking economy of Newton's methods.Subrahmanyan Chandrasekhar is one of the most reknowned scientists of the twentieth century, whose career spanned over 60 years. Born in India, educated at the University of Cambridge in England, he served as Emeritus Morton D. Hull Distinguished Service Professor of Theoretical Astrophysics at the University of Chicago, where he has was based from 1937 until his death in 1996. His early research into the evolution of stars is now a cornerstone of modern astrophysics, and earned him the Nobel Prize for Physics in 1983. Later work into gravitational interactions between stars, the properties of fluids, magnetic fields, equilibrium ellipsoids, and black holes has earned him awards throughout the world, including the Gold Medal from the Royal Astronomical Society in London, the National Medal of Science in the United States, and the Copley Medal from the Royal Society. His many publications include Radiative transfer, Hydrodynamic and hydromagnetic stability, and The mathematical theory of black holes, each being praised for its breadth and clarity. Newton's Principia for the common reader is the result of Professor Chandrasekhar's profound admiration for a scientist whose work he believed is unsurpassed, and unsurpassable. (shrink)

In the data collection phase, the digital images are captured using sensors that often contaminated by noise (undesired random signal). In digital image processing task, enhancing the image quality and reducing the noise is a central process. Image denoising effectively preserves the image edges to a higher extend in the flat regions. Several adaptive filters (median filter, Gaussian filter, fuzzy filter, etc.) have been utilized to improve the smoothness of digital image, but these filters failed to preserve the image edges (...) while removing noise. In this paper, a modified fuzzy set filter has been proposed to eliminate noise for restoring the digital image. Usually in fuzzy set filter, sixteen fuzzy rules are generated to find the noisy pixels in the digital image. In modified fuzzy set filter, a set of twenty-four fuzzy rules are generated with additional four pixel locations for determining the noisy pixels in the digital image. The additional eight fuzzy rules ease the process of finding the image pixels,whether it required averaging or not. In this scenario, the input digital images were collected from the underwater photography fish dataset. The efficiency of the modified fuzzy set filter was evaluated by varying degrees of Gaussian noise (0.01, 0.03, and 0.1 levels of Gaussian noise). For performance evaluation, Structural Similarity (SSIM), Mean Structural Similarity (MSSIM), Mean Square Error (MSE), Normalized Mean Square Error (NMSE), Universal Image Quality Index (UIQI), Peak Signal to Noise Ratio (PSNR), and Visual Information Fidelity (VIF) were used. The experimental results showed that the modified fuzzy set filter improved PSNR value up to 2-3 dB, MSSIM up to 0.12-0.03, and NMSE value up to 0.38-0.1 compared to the traditional filtering techniques. (shrink)

In this book, Christian Barry and Sanjay G. Reddy propose ways in which the international trading system can support poor countries in promoting the well-being of their peoples.

Comparative study of yoga philosophy of Vemana, Telugu poet and Vijñānabhairava, Hindu Tantric text.

Reflection Principles are commonly thought to produce only strong axioms of infinity consistent with V = L. It would be desirable to have some notion of strong reflection to remedy this, and we have proposed Global Reflection Principles based on a somewhat Cantorian view of the universe. Such principles justify the kind of cardinals needed for, inter alia , Woodin’s Ω-Logic.

About the Book : Several years ago, on a fateful night in a colonial house in Yercaud, Tamil Nadu, UG Krishnamurthi made a bonfire of Chandrasekhar's dreams.

In spite of the remarkable progress made in the burgeoning field of social neuroscience, the neural mechanisms that underlie social encounters are only beginning to be studied and could —paradoxically— be seen as representing the ‘dark matter’ of social neuroscience. Recent conceptual and empirical developments consistently indicate the need for investigations, which allow the study of real-time social encounters in a truly interactive manner. This suggestion is based on the premise that social cognition is fundamentally different when we are in (...) interaction with others rather than merely observing them. In this article, we outline the theoretical conception of a second-person approach to other minds and review evidence from neuroimaging, psychophysiological studies and related fields to argue for the development of a second-person neuroscience, which will help neuroscience to really go social; this may also be relevant for our understanding of psychiatric disorders construed as disorders of social cognition. (shrink)

Recent studies show that racism still exists in the American medical profession, the fact of which legitimizes the historically long-legacy of mistrust towards medical profession and health authorities among African Americans. Thus, it was suspected that the participation of black patients in end-of-life care has always been significantly low stemmed primarily from their mistrust of the medical profession. On the other hand, much research finds that there are other reasons than the mistrust which makes African Americans feel reluctant to the (...) end-of-life care, such as cultural-religious difference and genuine misunderstanding of the services. If so, two crucial questions are raised. One is how pervasive or significant the mistrust is, compared to the other factors, when they opt out of the end-of-life care. The other is if there is a remedy or solution to the seemingly broken relationship. While no studies available answer these questions, we have conducted an experiment to explore them. The research was performed at two Philadelphia hospitals of Mercy Health System, and the result shows that Black patients’ mistrust is not too great to overcome and that education can remove the epistemic obstacles as well as overcome the mistrust. (shrink)

Sri Aurobindo: the future -- Sri Aurobindo's contribution to humanity -- Sri Aurobindo's realisations -- Spirit & significance of Indian culture -- Sri Aurobindo's revelations.

The question of the relation between the collective and the individual has had a long but patchy history within both philosophy and psychology. In this chapter we consider some arguments that could be adopted for the primacy of the we, and examine their conceptual and empirical implications. We argue that the we needs to be seen as a developing and dynamic identity, not as something that exists fully fledged from the start. The concept of we thus needs more nuanced and (...) differentiated treatment than currently exists, distinguishing it from the idea of a ‘common ground’ and discerning multiple senses of ‘we-ness’. At an empirical level, beginning from the shared history of human evolution and prenatal existence, a simple sense of pre-reflective we-ness, we argue, emerges from second-person I-you engagement in earliest infancy. Developmentally, experientially and conceptually, engagement remains fundamental to the we throughout its many forms, characterized by reciprocal interaction and conditioned by the normative aspects of mutual addressing. (shrink)